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手机彩票网醫學院李曉明教授榮獲首屆CNS-CST杰出神經科學獎

來源:admin 發布日期:2019-08-09 訪問次數:73

中國神經科學學會評選,手机彩票网醫學院李曉明教授榮獲2019年度(首屆)CNS-CST杰出神經科學家獎,為獲此殊榮的兩位科學家之一。 

什么是CNS-CST杰出神經科學家獎?

為促進中國神經科學的發展,獎勵杰出科研人員,中國神經科學學會與Cell Signaling Technology(CST)中國共同設立了CNS-CST杰出神經科學家獎(CNS-CST Outstanding Neuroscientist Award)。該獎每兩年評選一次,每次評選兩人。今年是首次評選。

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李曉明教授簡介

李曉明,醫學博士,手机彩票网“求是”特聘教授,教育部“長江學者”特聘教授,“萬人計劃” 中青年創新領軍人才,國家杰出青年基金獲得者。現任手机彩票网醫學院常務副院長,手机彩票网神經科學研究所常務副所長,神經生物學系主任。2003年,畢業于原解放軍第一軍醫大學,獲得醫學博士學位。曾多年從事神經系統疾病的臨床,教學和科研工作。作為研究項目負責人,先后承擔了國家自然科學基金重點項目、重大科研計劃集成項目等。作為項目主要完成人,獲得國家自然科學獎二等獎,省科技進步一等獎,中國醫學科學二等獎,高等學校科研成果二等獎等。李曉明教授實驗室的研究主要是探究情感和情感障礙的神經環路和分子機制,近年來在突觸和神經環路的結構和功能調控領域,尤其在精神分裂癥、抑郁癥等精神疾病的發病機制方面取得重要研究成果,代表性論文以通訊作者發表在國際著名雜志如《Nature Medicine》、《Nature Neuroscience》、《Neuron》等上,并被國際同行發表專文正面評述。

近五年主要論著

1. Dong P, Wang H, Shen XF, Jiang P, ZhuXT,Li Y, Gao JH, Lin S, Huang Y,He XB, Xu FQ, Duan S,Lian H, Wang H,Chen J, LiXM*. A novel cortico-intrathalamic circuit for flight behavior. Nature Neuroscience.2019 Jun;22(6):941-949.

2. Shen CJ,Zheng D, Li KX, Yang JM, PanHQ, Yu XD, Fu JY,Zhu Y,Sun P,Xie Y,Duan S,Hu H, Li XM*. Cannabinoid CB1receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbensmodulate depressive-like behavior. Nature Medicine. 2019 Feb;25(2):337-349.

3. Li Y, Li CY, Xi W, Jin S, Wu ZH, JiangP, Dong P, He XB, Xu FQ, Duan SM, Zhou YD, Li XM*. Rostral and Caudal VentralTegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate inOpioid Dependence. Neuron. 2019 Feb 20;101(4):748-761. e5.

4. Yang JM,Shen CJ, Chen XJ,Kong Y, LiuYS, Li XW, Chen Z, Gao TM, Li XM*. erbb4 Deficits in Chandelier Cells in theMedial Prefrontal Cortex Confer Cognitive Dysfunctions: Implications for Schizophrenia.Cerebral Cortex. 2018 Dec 22. doi: 10.1093/cercor/bhy316.

5. Cao SX, Zhang Y, Hu XY, Hong B, Sun P,He HY, Geng HY, Bao AM, Duan SM, Yang JM, Gao TM, Lian H*, Li XM*. ErbB4deletion in noradrenergic neurons in the locus coeruleus induces mania-likebehavior via elevated catecholamines. eLife.2018 Sep 4;7.pill:e39907.

6. Geng HY, Jing Z, Yang JM, Li Y, Wang N,Ye M, Chen XJ, Lian H and Li XM*. Erbb4 Deletion from Medium Spiny Neurons ofthe Nucleus Accumbens Core Induces Schizophrenia-Like Behaviors via ElevatedGABAA Receptor α1 Subunit Expression. Journal of Neuroscience, 2017 Aug 2;37 (31): 7450-7464.

7. Zhu JM, Li KX, Cao SX,Chen XJ,ShenCJ,Zhang Y,Geng HY,Chen BQ,Lian H,Zhang JM,Li XM*.Increased NRG1-ErbB4signaling in human symptomatic epilepsy. Sientific Reports. 2017 Mar10;7(1):141.

8. Pan G,Yang JM,Hu XY,Li XM*. Postnatal development of the electrophysiological propertiesof somatostatin interneurons in the anterior cingulate cortex of mice.Scientific Reports. 2016 Jun 20;6:28137.

9. Zhang Y,Cao SX,Sun P,He HY,YangCH,Chen XJ,Shen CJ,Wang XD,Chen Z,Berg DK,Duan SM, Li XM*.Loss of MeCP2 incholinergic neurons causes part of RTT-like phenotypes via alpha7 receptor in hippocampus.Cell Research. 2016 Jun;26(6):728-42.

10. Ni KM, Hou XJ,Yang CH, Dong P,LiY,Zhang Y,Jiang P, Berg DK, DuanS,and Li XM*. Selectively driving cholinergicfibers optically in the thalamic reticular nucleus promotes sleep. eLife. 2016Feb 11;5.pii:e10382.

11. Lu YM, Gao YP, Tao RR, Liao MH,Huang JY, Wu G, Han F,Li XM*. Calpain-dependent ErbB4 cleavage is involved inbrain ischemia-induced neuronal death. Molecular Neurobiology. 2016 May;53(4):2600-9.

12. Pan G, Li Y, Geng HY, Yang JM, LiKX,Li XM*, Preserving GABAergic interneurons in acute brain slices of miceusing the N-methyl-D-glucamine-based artificial cerebrospinal fluidmethod.Neuroscience Bull. 2015 Apr;31(2),265-70.

13. Chen C, Li HQ, Liu YJ, Guo ZF, WuHJ, Li X, Lou HF, Zhu L, Wang D, Li XM, Yu L, Cao X, Lu L, GaoZ, DuanSM.A novelsizebased sorting mechanism of pinocytic luminal cargoes in microglia. Journal of Neuroscience. 2015 Feb 11;35(6):2674-88.